I think I have thoroughly disproved that over the years. The Similimum hits the energy field in about two seconds, (quote the Faculty of Homoeopathy video "Homoeopathy, the Realistic Alternative,") and works through the chakras into the endocrine glands and hormones, then into the Mental emotional and physical bodies more or less swiftly according to the patient's in-built nervous resistances. If I haven't had a happiness reaction in about 20 minutes I seriously doubt that I have given the right remedy.